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PREVAIL is a clinical research study evaluating the safety and effectiveness of an investigational drug in people who have cardiovascular disease.

The study drug is designed to lower cholesterol, specifically low-density lipoprotein cholesterol (LDL-C), known as the harmful or “bad” form of cholesterol.

Study overview:

• Have study clinic and telephone visits for about 3 to 4 years.
• Take 1 tablet of either the study drug or a placebo (no active ingredients) by mouth once daily.
• Continue taking your medication to lower cholesterol during the study that has been prescribed by your general practitioner (if applicable).
• Have 1 follow-up visit after your last dose of the assigned study drug or placebo (via telephone)

Key study requirements:

• You have a history of cardiovascular disease.
• You are 18 years of age or older and have elevated “bad” cholesterol levels:
• Fasting LDL-C of 100 mg/dL or greater

OR Fasting LDL-C of 80 to 100 mg/dL with at least 1 of the following risk factors:

• Recent heart attack (about 3 months ago to less than 1 year)
• Type 2 diabetes
• Other blood test results such as fasting triglycerides greater than 150 mg/dL, or fasting HDL-C less than 40 mg/dL (the “good” form of cholesterol)
• You are taking medication(s) to lower cholesterol (if applicable)

Note: Other requirements will apply.

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Study Locations

Accel Research Sites | Lake Oconee

119 Harmony Crossing
Eatonton, Georgia 31024

706-485-4004

Accel Research Sites | Deland

860 Peachwood Drive
DeLand, Florida 32720

386-785-2400